Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases
This article is a fantastic resource that looks at the nitty gritty of multiple signaling pathways. This is important because these pathways are the focus of research and pharmaceuticals companies to target these pathways for immune functions, inflammation, and anti-aging. Evid Based Complement Alternat Med. 2019; 2019: 2909632. Published online 2019 Jul 11. doi: 10.1155/2019/2909632 PMCID: PMC6657648 PMID: 31379957…
Read MoreToward the Existence of a Sympathetic Neuroplasticity Adaptive Mechanism Influencing the Immune Response. A Hypothetical View—Part I and II
I monitor autonomic activity in the clinic during acupuncture treatment. I use heart rate variability (HRV) and concentrate mostly on vagal activity or parasympathetic activity. But I’ve been impressed with the strength of the correlation of sympathetic activity with treatment, usually decreasing, with acupuncture and TAVNS also. I wasn’t aware that there was a…
Read MoreInflammation IL-6 , Electroacupuncture and HRV
This study, though older, is important because it connects the dots between vagal activity, pro-inflammatory cytokines (Il-6), and gastric emptying. It would be quite expensive to do this study in a human controlled trial. This is where these animal models are so useful to expand our thinking on how acupuncture works. http://www.ncbi.nlm.nih.gov/pubmed/23848593 Neurogastroenterol Motil. 2013…
Read MoreThe Sleep and Immunity: Crosstalk in Health and Disease
All of our systems are interrelated. This article looks in depth at the effect of sleep on the immune system. Very topical during or surviving from a pandemic! Sleep can affect how sick you get if infected, whether you get infected, and how well your immunization works for you. More on the topic of sleep…
Read MoreElectroacupuncture improves gut barrier dysfunction in prolonged hemorrhagic shock rats through vagus anti-inflammatory mechanism
The most important novel findings from this study are that when delayed resuscitation is inevitable during emergency situations such as hemorrhagic shock occurring in war without sufficient fluids, electroacupuncture at ST36 can be performed and it can successfully attenuate systemic inflammation, decrease gut injury and permeability and improve blood pressure and outcomes, which is consistent…
Read MoreReduced tactile acuity in chronic low back pain is linked with structural neuroplasticity in primary somatosensory cortex and is modulated by acupuncture therapy
This new article by friend of blog Vitaly Napadow shows improved tactile acuity after treatment with acupuncture for Low Back Pain. This is significant because “Previous neuroimaging studies have shown that other chronic pain disorders also demonstrate altered brain structure in S1, as well as other pain-related brain areas (As-Sanie et al., 2012, Kong et al.,…
Read MoreSpectral Analysis of Heart Rate Variability During Trigger-Point Acupuncture of Various Muscles
This group saw an increase in parasympathetic activity during trigger point acupuncture. This is probably a nonspecific effect of needling, but of significance nonetheless!! Spectral Analysis of Heart Rate Variability During Trigger-Point Acupuncture of Various Muscles Yoji Kitagawa Published Online: 27 Apr 2020 https://doi.org/10.1089/acu.2020.1414 Tools Share Abstract Objective: The aim of this research was to…
Read MorePain modulation in patients with fibromyalgia undergoing acupuncture treatment is associated with fluctuations in serum neuropeptide Y levels.
This is not a particularly new paper. I’ve somehow missed the data on Neuropeptide Y and its possible connection to acupuncture pain relief. https://www.ncbi.nlm.nih.gov/pubmed/28598785 Clin Exp Rheumatol. 2017 May-Jun;35 Suppl 105(3):81-85. Epub 2017 May 31. Pain modulation in patients with fibromyalgia undergoing acupuncture treatment is associated with fluctuations in serum neuropeptide Y levels. Iannuccelli C1,…
Read MoreAutonomic nervous system activation mediates the increase in whole-body glucose uptake in response to electroacupuncture.
I missed this relatively recent publication by Stener-Vitorin. Electroacupuncture stimulation for 40 minutes increases vagal activity, but also stimulated adipose metabolism via the sympathetic nervous system. The upshot was increased glucose uptake in patients with PCOS. FASEB J. 2017 Aug;31(8):3288-3297. doi: 10.1096/fj.201601381R. Epub 2017 Apr 12. Autonomic nervous system activation mediates the increase in whole-body…
Read MoreAnti-Inflammatory Effects of Acupuncture Stimulation via the Vagus Nerve
Anti-Inflammatory Effects of Acupuncture Stimulation via the Vagus Nerve Hee-Don Lim,1 Min-Hee Kim,1 Chan-Yong Lee,2 and Uk Namgung1,* Michal Hetman, Editor Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Associated Data Data Availability Statement Go to: Abstract Although acupuncture therapy is widely used in…
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