Deep Resilience: Chapter Stress Matters
I’ve “completed” another chapter in my long form writing project called “Stress Matters.” As blog readers know, I’ve been researching stress and monitoring autonomic nervous system activity in the clinic for many years. This chapter is still in a rough form, but I wanted to have some sense of completion so I can move on…
Read MoreStress and Tinnitus; Transcutaneous Auricular Vagal Nerve Stimulation Attenuates Tinnitus-Triggered Stress Reaction
Study from Helsinki on 171 patients. (Impressive! Especially given Finland’s small size.) It has a measure I’ve never seen before. ie. “HRV age”. Apparently the TAVNS decreased the patients’ HRV age by 9 years. Full article here. Front Psychol . 2020 Sep 17;11:570196. doi: 10.3389/fpsyg.2020.570196. eCollection 2020. Stress and Tinnitus; Transcutaneous Auricular Vagal Nerve Stimulation…
Read MoreSupraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338535/ Anesthesiology. Anesthesiology. 2019 Apr; 130(4): 651–665. Supraspinal Mechanisms of Spinal Cord Stimulation for Modulation of Pain: Five Decades of Research and Prospects for the Future Eellan Sivanesan, MD,1 Dermot Maher, MD, MS,1 Srinivasa N. Raja, MD,1 Bengt Linderoth, MD, PhD,2 and Yun Guan, MD, PhD1,3 Author information Copyright and License information Disclaimer Go to: Abstract The field of spinal cord stimulation…
Read MoreNumbers Needed to Treat
Numbers needed to treat. This is a crucial concept. It illustrates brilliantly the concept of First, Do No Harm, which also happens to be the title of the first chapter of my writing project “Deep Resilience”. This graphic comes from this excellent article with the even more excellent title when evidence says no but doctors…
Read MoreDeep Resilience. First Drafts of Introduction and Longevity Chapter
I am posting first drafts of two chapters from my writing project called Deep Resilience. The references haven’t been completed and there is plenty of polishing to do. I may add my own story to the Introduction, but for the sake of brevity left it out on this iteration. Introduction here Introduction-Deep Resilience-8.3.2020 Longevity Chapter for…
Read MoreAcupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain
This study is a bit complicated. They look at acupuncture at GB 34 and its effect on autophagy, dopamine and motor function in a mouse model of Parkinson’s condition. Though acupuncture increases autophagy of α-synuclein romoted the autophagic clearance of α-synuclein (α-syn), a well known aggregation-prone protein closely related to Parkinson’s disease (PD), in the…
Read MoreElectroacupuncture Enhances Number of Mature Oocytes and Fertility Rates for In Vitro Fertilization
Studies showing improved blood flow to the uterus with acupuncture are well known. This study shows improvement in number of mature ooctyes with electroacupuncture versus sham acupuncture. Med Acupunct. 2019 Oct 1; 31(5): 289–297. Published online 2019 Oct 17. doi: 10.1089/acu.2019.1368 PMCID: PMC6795274 PMID: 31624528 Electroacupuncture Enhances Number of Mature Oocytes and Fertility Rates for In Vitro Fertilization Ayu Cintani Kusuma,1 Nadia…
Read MoreEffects of Moxibustion on the Levels of Insulin-Like Growth Factor 1: A Pilot Study
I like this study especially because moxibustion can be applied by patients at home and via Insulin-Like Protein Growth Factor 1 (IGF-1) can improve insulin uptake and help longevity. Win win. Easy and safe. Effects of Moxibustion on the Levels of Insulin-Like Growth Factor 1: A Pilot Study Jaung-Geng Lin 1, Shinn-Zong Lin 2, Lih-Hwa Lin 3 4, Chun-Chang Wu 5, Wan-Ting Tsai 5, Horng-Jyh Harn 6, Li-Hui…
Read MoreElectro-acupuncture-induced neuroprotection is associated with activation of the IGF-1/PI3K/Akt pathway following adjacent dorsal root ganglionectomies in rats
This paper shows that acupuncture triggers IGF-1, a gene linked with longevity. Here it is involved in neuroplasticity following dorsal root ganglionectomies. Difficult to know if we can extrapolate to longevity genes in humans. Int J Mol Med. 2019 Feb; 43(2): 807–820. Published online 2018 Dec 18. doi: 10.3892/ijmm.2018.4035 PMCID: PMC6317683 PMID: 30569108 Electro-acupuncture-induced neuroprotection is…
Read MoreEffect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review
As part of the writing project I’m doing, I’m taking a deep dive into the molecular, biochemical processes set in motion by acupuncture. This is part of that effort. Int J Mol Sci . 2020 Jun 30;21(13):E4693. doi: 10.3390/ijms21134693. Effect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review…
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