Numbers Needed to Treat
Numbers needed to treat. This is a crucial concept. It illustrates brilliantly the concept of First, Do No Harm, which also happens to be the title of the first chapter of my writing project “Deep Resilience”. This graphic comes from this excellent article with the even more excellent title when evidence says no but doctors…
Read MoreDeep Resilience. First Drafts of Introduction and Longevity Chapter and Do No Harm
I am posting first drafts of two chapters from my writing project called Deep Resilience. The references haven’t been completed and there is plenty of polishing to do. I may add my own story to the Introduction, but for the sake of brevity left it out on this iteration. Introduction here Introduction-Deep Resilience-8.3.2020 Do No Harm…
Read MoreAcupuncture promotes mTOR-independent autophagic clearance of aggregation-prone proteins in mouse brain
This study is a bit complicated. They look at acupuncture at GB 34 and its effect on autophagy, dopamine and motor function in a mouse model of Parkinson’s condition. Though acupuncture increases autophagy of α-synuclein romoted the autophagic clearance of α-synuclein (α-syn), a well known aggregation-prone protein closely related to Parkinson’s disease (PD), in the…
Read MoreElectroacupuncture Enhances Number of Mature Oocytes and Fertility Rates for In Vitro Fertilization
Studies showing improved blood flow to the uterus with acupuncture are well known. This study shows improvement in number of mature ooctyes with electroacupuncture versus sham acupuncture. Med Acupunct. 2019 Oct 1; 31(5): 289–297. Published online 2019 Oct 17. doi: 10.1089/acu.2019.1368 PMCID: PMC6795274 PMID: 31624528 Electroacupuncture Enhances Number of Mature Oocytes and Fertility Rates for In Vitro Fertilization Ayu Cintani Kusuma,1 Nadia…
Read MoreEffects of Moxibustion on the Levels of Insulin-Like Growth Factor 1: A Pilot Study
I like this study especially because moxibustion can be applied by patients at home and via Insulin-Like Protein Growth Factor 1 (IGF-1) can improve insulin uptake and help longevity. Win win. Easy and safe. Effects of Moxibustion on the Levels of Insulin-Like Growth Factor 1: A Pilot Study Jaung-Geng Lin 1, Shinn-Zong Lin 2, Lih-Hwa Lin 3 4, Chun-Chang Wu 5, Wan-Ting Tsai 5, Horng-Jyh Harn 6, Li-Hui…
Read MoreElectro-acupuncture-induced neuroprotection is associated with activation of the IGF-1/PI3K/Akt pathway following adjacent dorsal root ganglionectomies in rats
This paper shows that acupuncture triggers IGF-1, a gene linked with longevity. Here it is involved in neuroplasticity following dorsal root ganglionectomies. Difficult to know if we can extrapolate to longevity genes in humans. Int J Mol Med. 2019 Feb; 43(2): 807–820. Published online 2018 Dec 18. doi: 10.3892/ijmm.2018.4035 PMCID: PMC6317683 PMID: 30569108 Electro-acupuncture-induced neuroprotection is…
Read MoreEffect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review
As part of the writing project I’m doing, I’m taking a deep dive into the molecular, biochemical processes set in motion by acupuncture. This is part of that effort. Int J Mol Sci . 2020 Jun 30;21(13):E4693. doi: 10.3390/ijms21134693. Effect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review…
Read MoreAnti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
I take Astragalus every day and so do many of my patients. This article is a good rundown of the health benefits. Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic Ping Liu,1 Haiping Zhao,1,# and Yumin Luo1,2,3,* Author information Article notes Copyright and License information Disclaimer This article has been cited by other…
Read MoreElectroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats
I’ve never heard the term “metainflammation” before, but I understand the concept. It refers to the global low-grade inflammation that can lead to so many issues, from heart disease, to cancer to cognitive decline. Sirt1 is a target of anti-aging research so I like to flag articles concerning Sirt1. Article here Evid Based Complement Alternat…
Read MoreSignal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases
This article is a fantastic resource that looks at the nitty gritty of multiple signaling pathways. This is important because these pathways are the focus of research and pharmaceuticals companies to target these pathways for immune functions, inflammation, and anti-aging. Evid Based Complement Alternat Med. 2019; 2019: 2909632. Published online 2019 Jul 11. doi: 10.1155/2019/2909632 PMCID: PMC6657648 PMID: 31379957…
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