David Sinclair Longevity Guru’s Failed Businesses
The article is worth a read if you’re interested and ends in this quote. “Sinclair said he believes that his companies will someday produce life-changing medicines. “Developing medicines that safely and effectively target aging,” he said, “is a difficult endeavor that has turned out to take longer than I expected.” I cited some of the…
Read MoreRapamycin for Anti-Aging: the latest science
From National Geographic: Rapamycin (red) inhibits a protein complex called mTORC1 (mammalian target of rapamycin complex 1, blue). It is mainly used to prevent rejection in organ transplantation, but some people are taking the drug for possible anti-aging benefits. So far, those benefits have not been proven in humans. (I wrote about MTOR in my…
Read MoreHow To Get Your Best Exercise
9 Key Takeaways on Exercise and Health Exercise Recommendations: Adults should aim for 150 minutes of moderate-intensity aerobic activity or 75 minutes of vigorous-intensity activity weekly, plus two days of muscle-strengthening exercises. Adjust these based on personal fitness goals and capabilities. Flexibility in Exercise: Physical activity doesn’t need to be gym-focused. Everyday activities like…
Read MoreSeasonal Affective Disorder: 6 tips on fixing It
Seasonal Depression, or SAD Seasonal Affective Disorder affects 5% of the population and for that population lasts 40% of the year (!!) This report from NPR talks about it. Location — and especially latitude — plays an important role. SAD is more common in people living far from the equator, which is why its…
Read MoreTAVNS and Chronic Knee Pain
We’ve discussed TAVNS or ear stimulation to increase vagal activity, here, here and here. This study is fascinating because it’s dealing with a condition that is “fixed”, ie, thought to be due to change in cartilage, and bone. Other pain types where is has been used, such as migraine are more episodic, multifactorial. Safety and…
Read MoreOld Friends and Early Life Stress
Thesis_Mazzari. old friends and stress pdf
Read MoreEye Masks and Why We Sleep from MantaSleep
This is from Manta Sleep. I bought a mask from them a month ago and my deep sleep has dramatically increased. For years, we’ve believed that better sleep and naps are the single best way to improve your performance and overall wellbeing. (More effective than any diet or exercise routine.) Turns out, the science backs…
Read MoreMind Magic by James Doty: Science of Manifestation
One of my classmates from Medical School published a popular book called Mind Magic by James Doty. It tells the tale of his overcoming an impoverished background in rural California, and becoming a wealthy neurosurgeon, only to have it all come crumbling down. Now, a professor at Stanford, he is head of the Dalai Lama…
Read MoreMood and ALAN, Artificial Light at Night
Get your sleep! Artificial Light At Night may be harming you! I monitor my sleep with an oura ring and I think it’s really paid off. After reading about the hazards of light pollution, I started using an eye mask from manta.com. My youtube on artificial light at night here. Menculini G, Cirimbilli F, Raspa…
Read MoreThe Avoidable Light That Might Shortening Your Life
This one was clearly off my radar. Here is my YouTube Video on the topic. But this hidden risk is somewhat easy to remedy, either by black out curtains and placing chargers in other rooms, or getting a well fitting and comfortable eye mask. I watched a short clip of an young actress, I wish…
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