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Why Southern Europeans Will Be the Longest Lived

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Metformin and anti-aging: a review

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Health & Fitness

Slow Aging, Huberman and David Sinclair

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Ethics in Medicine

Chemical Cocktail to Reverse Aging?

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Ethics in Medicine

Kaeberlein Withdrawing from Academy for Health and Lifespan Research

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Life Span by David Sinclair A science-based review of the world’s best-selling book on aging,

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Effects of transcutaneous auricular vagus nerve stimulation at left cymba concha on experimental pain, parasympathetic activity

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Medical Research

beneficial effects of honeybee-venom serum on facial wrinkles in humans

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Health & Fitness

Statins Neuromuscular Adverse Effects

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Health & Fitness

Acupuncture for primary insomnia: Effectiveness, safety, mechanisms and recommendations for clinical practice.

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Health & Fitness

Why Southern Europeans Will Be the Longest Lived

I’ve copied some of this article from the Economist.  It’s behind a paywall. Growing old together Why southern Europeans will soon be the longest-lived people in the world Diet and exercise, but also urban design and social life As patients and readers may know, I lived in Barcelona for three years when my children were…

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Medical Research

Metformin and anti-aging: a review

Metformin is already being taken by longevity hackers in the hopes that it will prolong their lives.  It remains to be seen and luckily there is a large trial underway to determine if it will help. Metformin does interfere with your body’s adapatation to physical activity.  In other words, it interferes with the hormesis of…

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Health & Fitness

Slow Aging, Huberman and David Sinclair

This is an Andrew Huberman episode with David Sinclair from a few years ago.  Sinclair is under fire lately for unprofessional, overblown claims.  I relied on his research for my chapter on Longevity in my book Radical Resilience, and so I have concerns about what his science actually shows!  I’ve blogged about Sinclair’s work here and…

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Ethics in Medicine

Chemical Cocktail to Reverse Aging?

Previous blog posts on David Sinclair here and here.  I relied on his research for my book Radical Resilience.  A brief video from my YouTube channel on the controversy. Review of new David Sinclair paper, supplements & anti-aging glitz

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Ethics in Medicine

Kaeberlein Withdrawing from Academy for Health and Lifespan Research

Matt Kaeberlein withdraws from the Academny for Health and Lifespan Research because of over blow claims by Sinclair After careful consideration, I have renounced my membership in the Academy for Health and Lifespan Research ( @ahlresearc ). I find it deeply distressing that we’ve gotten to a point where dishonesty in science is normalized to…

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Health & Fitness

Life Span by David Sinclair A science-based review of the world’s best-selling book on aging,

David Sinclair: ​ This blog post critically examines David Sinclair’s book “Life Span,” highlighting concerns about misinformation regarding longevity genes and the promotion of unproven supplements. I’m copying a rebuttal in full from 2023 to the ambitious claims laid out by David Sinclair in the TEDx talk below, and in his book “Life Span”.  I’ve…

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Medical Research

Effects of transcutaneous auricular vagus nerve stimulation at left cymba concha on experimental pain, parasympathetic activity

True prevention.  In my book I highlight two studies in animals where acupuncture prevented an increase in stress response after startling the animal.  This, to me, shows the power of prevention using acupuncture.  It stabilized your stress response to that you don’t spin out.  This is of utmost importance in understanding how acupuncture is so helpful…

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Medical Research

beneficial effects of honeybee-venom serum on facial wrinkles in humans

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598227/ The wrinkle depth decreased 10%.  I have no idea if that would be discernible.  The subjects in the study were  convinced it helped. Han SM, Hong IP, Woo SO, Chun SN, Park KK, Nicholls YM, Pak SC. The beneficial effects of honeybee-venom serum on facial wrinkles in humans. Clin Interv Aging. 2015 Oct 1;10:1587-92….

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Health & Fitness

Statins Neuromuscular Adverse Effects

Attardo S, Musumeci O, Velardo D, Toscano A. Statins Neuromuscular Adverse Effects. Int J Mol Sci. 2022 Jul 28;23(15):8364. doi: 10.3390/ijms23158364. PMID: 35955495; PMCID: PMC9369175. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369175/ Attardo S, Musumeci O, Velardo D, Toscano A. Statins Neuromuscular Adverse Effects. Int J Mol Sci. 2022 Jul 28;23(15):8364. doi: 10.3390/ijms23158364. PMID: 35955495; PMCID: PMC9369175. Statins are drugs widely…

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Health & Fitness

Acupuncture for primary insomnia: Effectiveness, safety, mechanisms and recommendations for clinical practice.

Primary insomnia (PI) is a growing concern, with cognitive-behavioral therapy as the first-line treatment, though accessibility and cost are issues. Hypnotics have risks and limited long-term effectiveness. Acupuncture is a potential treatment, showing improvements in subjective sleep quality, cognitive function, and emotional symptoms in clinical trials. It also enhances objective sleep measures and may restore…

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