Rapamycin for Anti-Aging: the latest science
From National Geographic: Rapamycin (red) inhibits a protein complex called mTORC1 (mammalian target of rapamycin complex 1, blue). It is mainly used to prevent rejection in organ transplantation, but some people are taking the drug for possible anti-aging benefits. So far, those benefits have not been proven in humans. (I wrote about MTOR in my…
Read MoreTAVNS and Chronic Knee Pain
We’ve discussed TAVNS or ear stimulation to increase vagal activity, here, here and here. This study is fascinating because it’s dealing with a condition that is “fixed”, ie, thought to be due to change in cartilage, and bone. Other pain types where is has been used, such as migraine are more episodic, multifactorial. Safety and…
Read MoreOld Friends and Early Life Stress
Thesis_Mazzari. old friends and stress pdf
Read MoreAcupuncture and Migraine: Combined with Beanembedding on Migraine and HRV
Nice study looking at acupuncture alone compared to acupuncture plus beanembedding. The beanembedding helped. Though there is supposed to be a free article, I can’t find it. Beanembedding is using of seeds instead of press needles in the ears. Of course, we’ve discussed migraine with acupuncture repeatedly on the blog! Lu Y, Sun Z, Huang…
Read MoreMind Magic by James Doty: Science of Manifestation
One of my classmates from Medical School published a popular book called Mind Magic by James Doty. It tells the tale of his overcoming an impoverished background in rural California, and becoming a wealthy neurosurgeon, only to have it all come crumbling down. Now, a professor at Stanford, he is head of the Dalai Lama…
Read MoreHallmarks of Aging: An Expanding Universe
This article has lots of detail about markers of aging. I’m not up to date on many of them, but some I’ve discussed before. I’ve covered telomeres, autophagy. And my book, Radical Resilience had an entire chapter on Longevity Science and Anti-Aging. Hallmarks of aging: An expanding universe López-Otín, Carlos et al. Cell, Volume 186,…
Read MoreMood and ALAN, Artificial Light at Night
Get your sleep! Artificial Light At Night may be harming you! I monitor my sleep with an oura ring and I think it’s really paid off. After reading about the hazards of light pollution, I started using an eye mask from manta.com. My youtube on artificial light at night here. Menculini G, Cirimbilli F, Raspa…
Read MoreArtificial Light at Night Increases Fat in Mice
Study showing that light at night can make fat cell growth worse. It disrupts melatonin and circadian rhythms, which has nasty effect on the body. Guan Q, Li Y, Wang Z, Cao J, Dong Y, Ren F, Chen Y. Monochromatic Light Pollution Exacerbates High-Fat Diet-Induced Adipocytic Hypertrophy in Mice. Cells. 2022 Nov 28;11(23):3808. doi: 10.3390/cells11233808….
Read MoreThe Avoidable Light That Might Shortening Your Life
This one was clearly off my radar. Here is my YouTube Video on the topic. But this hidden risk is somewhat easy to remedy, either by black out curtains and placing chargers in other rooms, or getting a well fitting and comfortable eye mask. I watched a short clip of an young actress, I wish…
Read MoreDoes Melatonin Prevent Alzheimer’s Disease?
You can watch my brief YouTube video on the topic here! The latest research from Rhonda Patrick on Melatonin and suggests that melatonin may prevent Alzheimer’s or at least add protection against it. And other ways it can help you. Different from Huberman! Melatonin isn’t just the “sleep hormone”—it regulates over 500 genes and plays…
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