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INS Barcelona 2022 HRV as Biomarker for Effective Clinical TAVNS

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Does transcutaneous auricular vagus nerve stimulation (TAVNS) affect vagally mediated heart rate variability (HRV)?

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Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

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The significance of “A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis

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Electroacupuncture Ameliorates Acute Pancreatitis: A Role for the Vagus Nerve-Mediated Cholinergic Anti-Inflammatory Pathway

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Identifying Dose Components of Manual Acupuncture to Determine the Dose–Response Relationship of Acupuncture Treatment: A Systematic Review

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Mast Cell-Mediated Mechanisms of Nociception.

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Astragalus and Longevity Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages.

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Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism

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Neuropeptides SP and CGRP Underlie the Electrical Properties of Acupoints.

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Medical Research

INS Barcelona 2022 HRV as Biomarker for Effective Clinical TAVNS

This is the abstract for my contribution to the International Neuromodulation Society World Congress in Barcelona May 21 to May 26th 2022. The post with a link to the actual poster is here.   HEART RATE VARIABILITY AS BIOMARKER FOR EFFECTIVE CLINICAL TRANSCUTANEOUS AURICULAR VAGAL NERVE STIMULATION: DIFFERENTIATING VAGAL VERSUS SYMPATHETIC ACTIVITY ­­ This case…

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Does transcutaneous auricular vagus nerve stimulation (TAVNS) affect vagally mediated heart rate variability (HRV)?

I wish I could say that I vehemently disagree with the conclusion of this literature review that TAVNS does not affect HRV.  As mentioned in this post, it is perhaps because it requires repeated attempts.  My studies in the clinic do not show decisive affect from TAVNS.  It is possible that I am asking the…

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Health & Fitness

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

I will be watching this ghrelin research carefully.  I’m a bit skeptical of this research that promises effortless weight loss.  On the other hand, I do believe that there are some powerful homeostatic mechanisms at play when the autonomic nervous system is stimulated.  As of now, the effects are muted but with the correct stimulation…

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The significance of “A neuroanatomical basis for electroacupuncture to drive the vagal-adrenal axis

This article is emphasizing the significance of this recent Nature article.  It is hard to overstate how groundbreaking the original article was.  We need better, more sophisticated ways to stimulate acupuncture points in order to get the maximum anti-inflammatory and parasympathetic effect. https://pubmed.ncbi.nlm.nih.gov/35128863/ Su YS, Li YM, Jing XH, Wang YQ, Han SP, Pan WX,…

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Electroacupuncture Ameliorates Acute Pancreatitis: A Role for the Vagus Nerve-Mediated Cholinergic Anti-Inflammatory Pathway

Still working on my Inflammation Chapter.  It is still a hot mess, but I may as well keep introduction this opaque term α7 nicotinic acetylcholine receptor (α7nAChR).  It comes up again and again and we all might as well familiarize ourselves with it.  It is actually exciting because acupuncture binds this receptor which leads to a…

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Identifying Dose Components of Manual Acupuncture to Determine the Dose–Response Relationship of Acupuncture Treatment: A Systematic Review

I have always wanted to study this topic.  I had thought that if I could make my HRV analysis extremely reliable, I would be able to gauge how effective a treatment was.  Maybe I still can!  But I am aware that manual acupuncture confers some advantages over electroacupuncture depending on the condition because of how…

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Mast Cell-Mediated Mechanisms of Nociception.

This article is an example of how all systems are interrelated.  It is a “law” that in my book I call “it all spins together.”  Here we see the close relationship between the immune system (mast cells) and nociception, or pain perception. I want to emphasize this quote from the article. ” 3. Role of…

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Health & Fitness

Astragalus and Longevity Astragalus membranaceus Injection Suppresses Production of Interleukin-6 by Activating Autophagy through the AMPK-mTOR Pathway in Lipopolysaccharide-Stimulated Macrophages.

This is a companion article to the previous astragalus article.  Though herbal therapy is not my focus, I have been taking an Astragulus compound for over a decade (when I remember, ha ha.)  It is a traditional anti-aging herb thought to have immune boosting properties as well.  I take Astra Essence from Health Concerns. My…

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Mitochondrial protection and anti-aging activity of Astragalus polysaccharides and their potential mechanism

I’m posting for reference.  There are issues with this article so that I’m not quite sure what to make of it.  One is that I think there is now some doubt about the free radical theory.  Two is that the mice were injected with an astragulus concentrate so perhaps not many conclusions can be drawn…

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Neuropeptides SP and CGRP Underlie the Electrical Properties of Acupoints.

It’s hard to know if this is super relevant, but it caught my eye because of the new, pricey, monthly injectable for migraine that targets CGRP.  Probably in no way pertinent, but I like to have this nonetheless.  Another article on acupoints here. AMA Fan Y, Kim DH, Ryu Y, et al. Neuropeptides SP and…

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