Electro-acupuncture-induced neuroprotection is associated with activation of the IGF-1/PI3K/Akt pathway following adjacent dorsal root ganglionectomies in rats
This paper shows that acupuncture triggers IGF-1, a gene linked with longevity. Here it is involved in neuroplasticity following dorsal root ganglionectomies. Difficult to know if we can extrapolate to longevity genes in humans. Int J Mol Med. 2019 Feb; 43(2): 807–820. Published online 2018 Dec 18. doi: 10.3892/ijmm.2018.4035 PMCID: PMC6317683 PMID: 30569108 Electro-acupuncture-induced neuroprotection is…
Read MoreThe Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol
Increased telomerase can lead to increased telomere length and improved life span. In this study they looked at the effect on telomerase with astragalus, an Ancient Chinese Medicine herbal remedy for longevity and danazol, a testosterone booster. The Astragalus had a more pronounced effect on telomerase than the danazol. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168059/ Biomedicines. 2020 Feb; 8(2): 31….
Read MoreNew Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach
Oxid Med Cell Longev. 2019; 2019: 4598167. Published online 2019 Dec 12. doi: 10.1155/2019/4598167 PMCID: PMC6930799 PMID: 31915506 New Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach Yanfei Liu, 1 , 2 Weiliang Weng, 2 Rui Gao, 2 and Yue Liu 3 Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract…
Read MoreVagus nerve stimulation boosts the drive to work for rewards
Not sure what to make of this study. But posting here because of the many and varied effects of the auricular branch of the vagus nerve. https://www.nature.com/articles/s41467-020-17344-9 Vagus nerve stimulation boosts the drive to work for rewards Monja P. Neuser, Vanessa Teckentrup, Anne Kühnel, Manfred Hallschmid, Martin Walter & Nils B. Kroemer Nature Communications volume 11,…
Read MoreEffect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review
As part of the writing project I’m doing, I’m taking a deep dive into the molecular, biochemical processes set in motion by acupuncture. This is part of that effort. Int J Mol Sci . 2020 Jun 30;21(13):E4693. doi: 10.3390/ijms21134693. Effect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review…
Read MorePractical applications of chaos theory to the modulation of human ageing: nature prefers chaos to regularity
We discussed the concept of complexity with aging here. This article reinforces that principle. The full article is behind a paywall and since it’s an older article, I will skip the purchase and just cite the article. https://link.springer.com/article/10.1023/A:1023306419861 Published: March 2003 Practical applications of chaos theory to the modulation of human ageing: nature prefers chaos…
Read MoreAnti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
I take Astragalus every day and so do many of my patients. This article is a good rundown of the health benefits. Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic Ping Liu,1 Haiping Zhao,1,# and Yumin Luo1,2,3,* Author information Article notes Copyright and License information Disclaimer This article has been cited by other…
Read MoreElectroacupuncture: A Feasible Sirt1 Promoter Which Modulates Metainflammation in Diet-Induced Obesity Rats
I’ve never heard the term “metainflammation” before, but I understand the concept. It refers to the global low-grade inflammation that can lead to so many issues, from heart disease, to cancer to cognitive decline. Sirt1 is a target of anti-aging research so I like to flag articles concerning Sirt1. Article here Evid Based Complement Alternat…
Read MoreSignal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases
This article is a fantastic resource that looks at the nitty gritty of multiple signaling pathways. This is important because these pathways are the focus of research and pharmaceuticals companies to target these pathways for immune functions, inflammation, and anti-aging. Evid Based Complement Alternat Med. 2019; 2019: 2909632. Published online 2019 Jul 11. doi: 10.1155/2019/2909632 PMCID: PMC6657648 PMID: 31379957…
Read MoreWear the Humble Mask. It Is Your Servant to Protect and Defend
There will be no improvement in jobs and economic activity until we beat this thing. Until infection rates in whatever population decreases to manageable levels, we will be stuck with no “normal” life. From California we cannot visit New York without quarantining anymore. Though deaths are staying flat, hospitalizations are increasing. In the Bay Area…
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