Tag: systems biology
Senescent cells and the incidence of age-related diseases
This article is from the Lab of Uri Alon looking at senescent cells in several age-related diseases. I am a follower of Alon for a few reasons. 1. He has extremely helpful youtubes on choosing a scientific project, how to pose a good scientific question, and how to give a good talk . I think…
Read MoreSystems Medicine 2020 Uri Alon
I am stashing this link and series of links here since systems biology is very much a part of acupuncture and its results. Small input of needling can lead to outsized results a consequence of the cascades set in motion. I’m working on the Immunology Chapter of my book “Deep Resilience” and I will need…
Read MoreNetwork, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system
Fascinating background material for my chapter on the Immune System Tieri P, Grignolio A, Zaikin A, et al. Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system. Theor Biol Med Model. 2010;7:32. Published 2010 Aug 11. doi:10.1186/1742-4682-7-32 Abstract Recently, the network paradigm, an application of graph theory to…
Read MoreHPA-leptin axis and metabolic health: a systems approach to resilience
There is intense focus on metabolic syndrome and obesity in the last decade or two. This study is trying to get at categorizing the hypothalamic-pituitary-adrenal-leptin responses in obese women vis a vis their fat and lean body mass and their insulin resistance. This study is another “systems biology” investigation. Interface Focus. 2014 Oct 6; 4(5):…
Read MoreCharacterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements
This article is from 2012, but I had never seen it. It seeks to quantify different chemical profiles of rheumatoid arthritis patients according to their Chinese Medicine profiles. Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements Herman A. van Wietmarschen , Weidong Dai , Anita J. van der Kooij…
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