Vagus nerve stimulation boosts the drive to work for rewards

Kristen Sparrow • July 20, 2020

Vagus nerve stimulation boosts the drive to work for rewards

Not sure what to make of this study.  But posting here because of the many and varied effects of the auricular branch of the vagus nerve.

https://www.nature.com/articles/s41467-020-17344-9

Vagus nerve stimulation boosts the drive to work for rewards

Abstract

Interoceptive feedback transmitted via the vagus nerve plays a vital role in motivation by tuning actions according to physiological needs. Whereas vagus nerve stimulation (VNS) reinforces actions in animals, motivational effects elicited by VNS in humans are still largely elusive. Here, we applied non-invasive transcutaneous auricular VNS (taVNS) on the left or right ear while participants exerted effort to earn rewards using a randomized cross-over design (vs. sham). In line with preclinical studies, acute taVNS enhances invigoration of effort, and stimulation on the left side primarily facilitates invigoration for food rewards. In contrast, we do not find conclusive evidence that acute taVNS affects effort maintenance or wanting ratings. Collectively, our results suggest that taVNS enhances reward-seeking by boosting invigoration, not effort maintenance and that the stimulation side affects generalization beyond food reward. Thus, taVNS may enhance the pursuit of prospective rewards which may pave avenues to treat motivational deficiencies.