Tag: longevity
Electro-acupuncture-induced neuroprotection is associated with activation of the IGF-1/PI3K/Akt pathway following adjacent dorsal root ganglionectomies in rats
This paper shows that acupuncture triggers IGF-1, a gene linked with longevity. Here it is involved in neuroplasticity following dorsal root ganglionectomies. Difficult to know if we can extrapolate to longevity genes in humans. Int J Mol Med. 2019 Feb; 43(2): 807–820. Published online 2018 Dec 18. doi: 10.3892/ijmm.2018.4035 PMCID: PMC6317683 PMID: 30569108 Electro-acupuncture-induced neuroprotection is…
Read MoreThe Use of Natural Agents to Counteract Telomere Shortening: Effects of a Multi-Component Extract of Astragalus mongholicus Bunge and Danazol
Increased telomerase can lead to increased telomere length and improved life span. In this study they looked at the effect on telomerase with astragalus, an Ancient Chinese Medicine herbal remedy for longevity and danazol, a testosterone booster. The Astragalus had a more pronounced effect on telomerase than the danazol. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7168059/ Biomedicines. 2020 Feb; 8(2): 31….
Read MoreNew Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach
Oxid Med Cell Longev. 2019; 2019: 4598167. Published online 2019 Dec 12. doi: 10.1155/2019/4598167 PMCID: PMC6930799 PMID: 31915506 New Insights for Cellular and Molecular Mechanisms of Aging and Aging-Related Diseases: Herbal Medicine as Potential Therapeutic Approach Yanfei Liu, 1 , 2 Weiliang Weng, 2 Rui Gao, 2 and Yue Liu 3 Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract…
Read MoreMetformin for Anti Aging
There has been buzz about Metformin as a possible tool to deter aging. On principle I’m opposed to these specific, medication related strategies because I think they can be dangerous, or at least have side effects that are unwanted. The reason I’m posting this, is that it has the details on how it’s supposed to…
Read MoreComplexity and Aging
As readers know, I’m focused on Heart Rate Variability in the clinic. It is a perfect example of the complexity this author is talking about. Within bounds, more variability in heart rate is healthier and and leads to more resilience. I wonder about this quite a bit, whether people’s habits get more routine with age. …
Read MoreSleep. The Best Medicine
Besides laughter of course! Add the above physical and mental health consequences up, and a scientifically validated link becomes easier to accept: the shorter your sleep, the shorter your life. Recent findings demonstrate that individuals who routinely sleep five hours a night have a 65 percent increased risk of dying at any moment in…
Read MoreWarm Needle Acupuncture Shows Anti-Aging Effects in Animals
This study looks at moxibustion, warm needle moxibustion in elderly rats to see effect on their gonads. It appears that there is an anti-aging effect in the testes which originates in the pituitary. Since the HPA (hypothalamic-pituitary-adrenal) axis is key in stress response, this, of course interests me. Also because of acupuncture’s claims in leading…
Read MoreLife in the Fast Lane Kills: Mitochondria and Longevity
A fascinating interview, and not too technical, by an expert who studies longevity. Please read the whole thing, but these two excerpts below bring up some interesting concepts that might be counter-intuitive. The first is that anti-oxidants if taken as a supplement can actually lead to more free radicals. The second is that fruits and…
Read MoreAutophagy for Life Extension: Rhonda Patrick
Rhonda Patrick’s blog is focused on longevity research. She is a biochemist by training, but now devotes her time to making the arcane world of biochemisty research on aging accessible to the lay public. (In a recent podcast she discussed how she came to the decision to turn down a tenure track professorship at a…
Read MoreMeditation, Monks, Nuns and Telomeres
An article from the San Francisco Chronicle hightlights research that has been ongoing on meditation and brain function. In this article they focus on studies being done at Stanford using fMRI on experienced meditators and what happens to their brains. For those interested in the details, please click through to the article. Again, I’m far…
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