%PDF-1.3
%
17 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
11 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
4 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
1 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
3 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
18 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
12 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
6 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
10 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
13 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
5 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
16 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
14 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
8 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 53/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0 q-Br44C@B 9 s
(P
endstream
endobj
15 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
7 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
9 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 54/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T R
Ɩf
!\!Y\ !p )P
endstream
endobj
19 0 obj
<>>>/Subtype/Form/BBox[0 0 612 792]/Matrix [1 0 0 1 0 0]/Length 55/FormType 1/Filter/FlateDecode>>stream
xs
w3T04PI2P0T5T0P02S04S @$P5 )1
endstream
endobj
21 0 obj
<>stream
Acrobat Distiller 8.1.0 (Windows); modified using iText 4.2.0 by 1T3XT
Arbortext Advanced Print Publisher 9.0.114/W
2015-10-20T08:40:34-07:00
2015-10-07T14:48:49+05:30
application/pdf
ACM-2015-0078-ver9-Doo_4P 598..603
uuid:e2a1b142-c1e3-432e-b102-ffd32f02a028
uuid:77237b2f-b152-40b5-8942-4015c105c952
endstream
endobj
22 0 obj
<>stream
x+ |
endstream
endobj
23 0 obj
<>stream
xS**T0T0 BiU)D* 9V
endstream
endobj
24 0 obj
<>stream
x+ |
endstream
endobj
25 0 obj
<>stream
xS**T0T0 Bih] D. pa
endstream
endobj
26 0 obj
<>stream
x+ |
endstream
endobj
27 0 obj
<>stream
xS**T0T0 BiUD* :
endstream
endobj
28 0 obj
<>stream
x+ |
endstream
endobj
29 0 obj
<>stream
xS**T0T0 BiUD* 8
endstream
endobj
30 0 obj
<>stream
x+ |
endstream
endobj
31 0 obj
<>stream
xS**T0T0 Bih]9D. qaj
endstream
endobj
32 0 obj
<>stream
x+ |
endstream
endobj
33 0 obj
<>stream
xS**T0T0 BiU !D. _e1
endstream
endobj
36 0 obj
<>stream
/GS1 gs
BT
/F5 1 Tf
9.843 0 0 9.843 59.7543 725.1588 Tm
0 0 0 1 k
0 Tc
0 Tw
[(ne)19.7(ur)15.1(oi)20.7(ma)18.4(gi)20.7(ng)-203.8(de)19.7(mo)19.6(ns)21(tr)15(at)19.5(ed)-205(th)20.7(at)-205.1(ac)18.5(up)20.8(un)15.1(ct)19.5(ur)20.9(e)-215.4(s)0(t)20.9(i)0(m)19.5(u)0(l)20.7(a)0(t)13.8(i)0(o)20.7(n)0(s)-203.6(c)0(a)18.5(n)]TJ
0 -1.1174 TD
[(ac)18.5(ti)14.8(va)19.7(te)-291.5(ne)19.7(ur)15.1(al)-291.5(re)19.7(sp)15.3(on)20.8(se)19.9(s)-306.2(i)0(n)-290.3(b)0(r)20.9(a)0(i)13.8(n)-300.6(re)19.7(gi)20.7(on)15.1(s,)-292.3(in)20.7(cl)19.5(ud)20.8(in)20.7(g)-306.4(t)0(h)20.7(e)-307.5(su)21(b-)]TJ
0 -1.1116 TD
[(st)15.1(an)19.7(ti)20.6(a)-411.2(n)0(i)20.7(g)0(r)20.9(a)0(,)-403.1(c)0(a)18.5(u)0(d)20.8(a)0(t)19.5(e)0(,)-403.1(t)0(h)20.7(a)0(l)19.5(a)0(m)18.5(u)0(s)15.3(,)-406.6(an)19.7(d)-410(p)0(u)15.1(t)0(a)19.6(m)0(e)18.4(n)0(,)-396.2(t)0(h)15(a)0(t)-400.9(a)0(r)19.7(e)-411.2(im)19.5(-)]TJ
T*
[(pa)19.7(ir)15(ed)-262.5(in)-261.5(PD)20.1(.)]TJ
7.3823 0 0 6.5614 111.5716 696.6423 Tm
(15)Tj
9.843 0 0 9.843 121.5496 692.277 Tm
[(Re)18.6(ce)18.5(nt)14.9(ly)20.7(,)-268.4(b)0(e)19.7(e)-273(ve)19.7(no)20.8(m)-273(a)0(c)18.5(u)0(p)20.8(u)0(n)20.8(c)0(t)13.8(u)0(r)20.9(e)-273(\(B)19.8(VA)19.1(\))-271.8(h)0(a)19.7(s)]TJ
-6.2781 -1.1116 TD
[(be)19.7(co)13.9(m)15(e)-405.4(a)-399.7(t)0(r)20.7(e)0(a)12.8(t)0(m)25.2(e)0(n)13.9(t)-398.6(fo)20.9(r)-404.2(n)0(e)19.7(u)0(r)20.9(o)0(d)20.8(e)0(g)19.7(e)0(n)19.7(e)0(r)19.7(a)0(t)13.8(i)0(v)20.7(e)-399.7(di)20.7(se)19.9(as)14.1(es)-389.1(su)21(ch)-395(as)]TJ
0 -1.1174 TD
[(PD)14.4(.)-314.5(S)0(e)19.8(v)0(e)19.7(r)0(a)19.7(l)-312.2(st)15.1(ud)20.8(ie)19.6(s)-311.9(h)0(a)19.7(v)0(e)-308.6(d)0(e)19.7(m)0(o)19.6(n)0(s)21(t)0(r)20.7(a)0(t)13.8(e)0(d)-302.9(t)0(h)20.7(a)0(t)-308.8(B)0(V)18.9(A)-313(ha)19.7(s)-317.7(n)0(e)19.7(u)0(r)20.9(o)0(-)]TJ
0 -1.1116 TD
[(pr)15.1(ot)20.7(ec)18.5(ti)20.6(ve)19.7(,)-360.5(a)0(n)19.7(t)0(i)20.6(-)0(a)14(p)0(o)20.8(p)0(t)20.7(o)0(t)20.7(i)0(c)19.6(,)-360.5(an)19.7(d)-364(a)0(n)19.7(t)0(i)20.6(-)0(i)20.7(n)0()21(a)0(m)18.5(m)0(a)18.5(t)0(o)20.7(r)0(y)-353.5(e)0(f)19.7(f)0(e)19.7(c)0(t)19.6(s)-363.8(th)20.7(at)]TJ
T*
-.0201 Tc
[(c)-20.1(a)-1.6(n)-291.9(r)-20.1(ed)-20.1(uc)-20.1(e)-283.8(d)-20.1(am)-20.1(ag)-20.1(e)-282.6(t)-20.1(o)-281.6(d)-20.1(op)-20.1(am)-20.1(in)-20.1(er)-20.1(gi)-20.1(c)-282.8(n)-20.1(eu)-20.1(ro)-20.1(ns)-20.1(.)]TJ
7.3823 0 0 6.5614 236.4094 652.8187 Tm
0 Tc
[(16)24.7(1)24.7(9)]TJ
9.843 0 0 9.843 69.7323 637.455 Tm
[(In)-393.8(a)-393.9(previous)-395.8(clinical)-398.7(trial)-398.7(we)-390.1(conducted,)]TJ
7.3823 0 0 6.5614 239.3007 641.877 Tm
(20)Tj
9.843 0 0 9.843 250.5826 637.455 Tm
(acupuncture)Tj
-19.3872 -1.1116 TD
[(and)-597.7(BVA)-593.6(each)-595.4(showed)-590.2(promising)-598.7(results)-590.4(as)-596.4(adjunctive)]TJ
T*
[(therapies)-451.2(for)-446.7(idiopathic)-451.6(PD.)-444.1(In)-445.7(a)-445.8(clinical)-450.6(setting,)-444.5(BVA)-449.6(is)]TJ
0 -1.1174 TD
[(usually)-440.9(combined)-438.7(with)-437.5(manual)-442.3(acupuncture.)-440.8(However,)-441.4(no)]TJ
0 -1.1116 TD
[(clinical)-289.3(studies)-291(have)-289(assessed)-288(the)-286.8(effectiveness)-290.6(of)-290.2(combined)]TJ
T*
[(treatment)-400.9(with)-397.2(acupuncture)-397(and)-396.1(BVA)-397.7(for)-394.9(PD.)-392.2(The)-397.3(current)]TJ
T*
[(prospective)-9.9(,)-239.6(open-label,)-254.3(self-controlled)-250.6(study)-247.3(was)-247(conducted)]TJ
0 -1.1174 TD
[(to)-353.7(investigate)-361.5(the)-350.2(effectiveness)-359.8(and)-355.8(safety)-354.4(of)-353.5(the)-355.9(combined)]TJ
0 -1.1116 TD
[(treatment)-337.5(as)-337.2(an)-331.7(adjunctive)-337.4(treatment.)]TJ
/F3 1 Tf
8.9663 0 0 8.9663 59.7543 525.8833 Tm
[(Materials)-339(and)-331.9(Methods)]TJ
/F9 1 Tf
0 -1.8336 TD
[(Ethics)-337(approval)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 493.0014 Tm
[(The)-345.5(study)-345.3(was)-350.7(done)-345.4(in)-342.1(accordance)-352(with)-345.4(the)-344.4(ethical)-351.4(stan-)]TJ
-1.0137 -1.1116 TD
[(dards)-380.8(of)-376.5(the)-379(Helsinki)-379.7(Declaration.)-378.5(The)-380(institutional)-379.1(review)]TJ
T*
[(board)-640.2(of)-635.7(the)-638.2(university)-640.2(hospital)-638(approved)-638.9(the)-638.2(protocol)]TJ
0 -1.1174 TD
[(\(KHNMC-OH-IRB-20)-14.3(12-01-013\).)-394.5(After)-399.3(being)-392.7(given)-398.5(a)-399.7(full)]TJ
0 -1.1116 TD
[(description)-469.6(of)-462.9(the)-465.4(study,)-463.9(all)-465.5(participants)-472(provided)-465.1(written)]TJ
T*
[(informed)-339.6(consent.)]TJ
/F9 1 Tf
8.9663 0 0 8.9663 59.7543 414.3117 Tm
[(Patient)-337.7(recruitment)-336.9(and)-329.4(selection)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 397.8708 Tm
[(Th)19.6(is)-353.5(st)15.1(ud)20.8(y)-364(t)0(o)20.7(o)0(k)-353.5(p)0(l)20.7(a)0(c)18.5(e)-365.1(be)19.7(tw)19.8(ee)18.5(n)-364(N)0(o)14.2(v)0(e)19.7(m)0(b)19.6(e)0(r)-354.7(2)0(0)20.8(1)0(2)-353.5(a)0(n)19.7(d)-364(Ma)18.8(y)]TJ
-1.0137 -1.1116 TD
[(20)15.1(14)-255.6(at)-262.7(Ky)20(un)20.8(g)-271.8(H)0(e)18.8(e)-273(Un)20(iv)20.7(er)19.7(si)15.1(ty)-255.8(Ho)20(sp)15.3(it)20.6(al)-262.7(at)-256.9(Ga)18.8(ng)15.1(do)20.8(ng)20.8(,)-268.4(K)0(o)20(r)0(e)19.7(a)0(.)]TJ
0 -1.1174 TD
[(Pa)14.1(rt)20.7(ic)19.6(ip)20.7(an)19.7(ts)-388(we)18.8(re)-383.5(re)19.7(cr)19.7(ui)14.9(te)19.6(d)-392.8(t)0(h)20.7(r)0(o)20.9(u)0(g)20.8(h)-398.5(th)20.7(e)-393.9(u)0(n)20.8(i)0(v)15(e)0(r)19.7(s)0(i)20.9(t)0(y)20.7()0(s)-387.9(w)0(e)18.8(b)0(s)21(i)0(t)20.6(e)]TJ
0 -1.1116 TD
[(an)19.7(d)-427.3(b)0(u)20.8(l)0(l)20.6(e)0(t)19.5(i)0(n)-417(b)0(o)20.8(a)0(r)19.7(d)0(s)15.3(.)-423.9(In)20.9(te)19.6(re)19.7(st)20.9(ed)-418.1(pa)19.7(ti)20.6(en)19.7(ts)-416.8(co)19.7(nt)20.7(ac)18.5(te)19.6(d)-427.3(t)0(h)20.7(e)-428.5(st)20.9(ud)20.8(y)]TJ
T*
[(co)19.7(or)15.1(di)20.7(na)19.7(to)20.7(r)-600.1(f)0(o)20.9(r)-605.8(fu)20.9(rt)20.7(he)19.7(r)-600.1(i)0(n)20.7(f)0(o)15.1(r)0(m)19.6(a)0(t)19.5(i)0(o)20.7(n)0(.)-592(P)0(o)21(t)0(e)19.6(n)0(t)20.7(i)0(a)19.6(l)-600.2(pa)19.7(rt)15(ic)19.6(ip)20.7(an)19.7(ts)]TJ
0 -1.1174 TD
[(we)18.8(re)-314.4(th)15(en)-308.6(of)15.1(fe)19.7(re)19.7(d)-323.6(a)-324.8(fo)20.9(rm)19.6(al)-314.5(in)20.7(-p)20.9(er)19.7(so)15.3(n)-317.9(a)0(s)14.1(s)0(e)19.9(s)0(s)21.2(m)0(e)18.4(n)0(t)20.7(.)]TJ
/F9 1 Tf
8.9663 0 0 8.9663 59.7543 319.6913 Tm
[(Inclusion)-336.7(and)-335.7(exclusion)-332.6(criteria)]TJ
/F5 1 Tf
9.843 0 0 9.843 69.7323 303.2503 Tm
[(Inclusion)-385.5(criteria)-387(were)-387.7(as)-389.1(follows:)-384.2(\(1\))-383.4(diagnosis)-385.3(of)-388.1(with)]TJ
-1.0137 -1.1174 TD
[(idiopathic)-543.8(PD)-538.6(according)-537.6(to)-538(the)-540.2(UK)-533.8(Parkinsons)-542.7(Disease)]TJ
0 -1.1116 TD
[(Society)-292.4(Brain)-284.3(Bank)-288.8(criteria;)]TJ
7.3823 0 0 6.5614 171.4393 285.6755 Tm
(21)Tj
9.843 0 0 9.843 181.644 281.3102 Tm
[(\(2\))-285.5(receipt)-287.9(of)-290.2(a)-284.5(stable)-285.5(dose)-287.6(of)]TJ
-12.3834 -1.1116 TD
[(anti-parkinsonian)-293.2(medication)-286.8(for)-285.5(at)-285.7(least)-284.4(4)-283.3(weeks)-285(before)-285.3(the)]TJ
0 -1.1174 TD
[(trial;)-434.5(\(3\))-429.5(stage)-434(14)-429.5(PD)-429.1(accor)-9(ding)-425(to)-434.3(the)-430.8(Hoehn)-433.8(and)-430.7(Yahr)]TJ
0 -1.1116 TD
(scale;)Tj
7.3823 0 0 6.5614 82.3181 252.7936 Tm
(22)Tj
9.843 0 0 9.843 93.5433 248.4283 Tm
[(\(4\))-389.1(score)-387.7(of)-388.1(greater)-391.4(than)-385.8(1)-387(point)-391.7(in)-382.5(2)-387(o)0(r)-388.1(more)-386.9(ca-)]TJ
-3.4328 -1.1116 TD
[(tegories)-460.4(on)-457.2(the)-459.6(Unied)-457.9(Parkinsons)-462.1(Disease)-461.1(Rating)-458.3(Scale)]TJ
0 -1.1174 TD
[(\(UPDRS\))-482.4(part)-478(III,)-473.2(including)-478(tremor,)-479(rigidity,)-479.3(postural)-476.5(in-)]TJ
0 -1.1116 TD
[(stability,)-539.1(and)-540.1(bradykinesia;)-536.4(and)-540.1(\(5\))-533.1(a)-537.9(Mini-Mental)-540.9(State)]TJ
T*
[(ExaminationKorean)-344.9(version)-331.3(score)-335.9(greater)-339.6(than)-334(24.)]TJ
26.5234 52.8856 TD
[(Exclusion)-409.8(criteria)-410(were)-416.5(as)-406.3(follows:)-413(\(1\))-406.4(having)-411.1(epilepsy,)]TJ
-1.0137 -1.1174 TD
[(dementia,)-489.5(alcohol)-488.4(or)-486(drug)-488.2(addiction)-490.7(and)-482.5(having)-491.7(received)]TJ
0 -1.1116 TD
[(psychiatric)-361.4(medication;)-357.2(\(2\))-354.6(secondary)-364.5(parkinsonism)-355.3(caused)]TJ
T*
[(by)-537.9(cerebrovascular)-541.7(disease,)-544.3(neoplasm,)-539.9(and)-540.1(infection;)-543.7(\(3\))]TJ
T*
[(Parkinson-plus)-263.9(syndromes;)-260.8(\(4\))-256.7(pregnancy;)-262.3(and)-257.9(\(5\))-262.4(a)-261.4(positive)]TJ
0 -1.1174 TD
[(result)-336.1(on)-330.5(a)-336.3(bee)-333.9(venom)-336.2(skin)-332.6(allergy)-332.8(test.)]TJ
1.0137 -1.1116 TD
[(Dropout)-279.4(criteria)-277.6(were)-284(the)-281.1(following:)-277.3(\(1\))-279.7(skipping)-279.6(of)-278.6(more)]TJ
-1.0137 -1.1116 TD
[(than)-460.7(8)-461.9(o)0(f)-457.2(the)-465.4(24)-457.2(total)-462.1(treatment)-464.2(sessions,)-462(\(2\))-464(serious)-463.6(ab-)]TJ
0 -1.1174 TD
[(normal)-377.7(reactions,)-385.5(and)-378.8(\(3\))-377.6(withdrawal)-384.1(of)-382.3(agreement)-384.5(to)-376.7(par-)]TJ
0 -1.1116 TD
[(ticipate)-335.4(in)-336.4(the)-332.9(study.)]TJ
/F9 1 Tf
8.9663 0 0 8.9663 310.8472 599.1306 Tm
[(Study)-332.3(protocol)]TJ
/F5 1 Tf
9.843 0 0 9.843 320.8251 582.6896 Tm
[(This)-351.1(study)-351(was)-356.5(a)-347.8(prospe)-7.5(ctive,)-351.3(open-label,)-358(self-controlled)]TJ
-1.0137 -1.1116 TD
[(trial.)-235.1(All)-240.6(participants)-241.6(were)-238(assessed)-241.9(by)-232.6(using)-235.8(UPDRS)-238.4(parts)-242.7(II)]TJ
0 -1.1174 TD
[(and)-580.4(III,)-576.8(the)-580.6(Parkinsons)-577.3(Disease)-582(Quality)-586.1(of)-578.1(Life)-577.1(Ques-)]TJ
0 -1.1116 TD
[(tionnaire)-479.1(\(PDQL\),)-485.1(the)-476.9(Beck)-485.8(Depression)-480.5(Inventory)-483.4(\(BDI\),)]TJ
T*
[(postural)-269.2(stability,)-274.2(and)-269.4(the)-269.5(time)-266.2(and)-269.4(number)-273.9(of)-267.1(steps)-271.4(required)]TJ
0 -1.1174 TD
[(to)-474.6(walk)-478.9(20)-163.5(m.)-478.1(Patients)-477.7(maintained)-476.9(their)-479.2(anti-parkinsonian)]TJ
0 -1.1116 TD
[(medication)-407.8(without)-400.6(any)-407.6(additional)-405.5(treatment)-406.7(for)-406.4(12)-399.6(weeks)]TJ
T*
[(\(conventional)-461.7(treatment\).)-468.8(After)-456.9(this,)-462.9(patients)-466.4(were)-462.6(treated)]TJ
0 -1.1174 TD
[(with)-426(acupuncture)-437.3(and)-424.9(BVA)-432.3(\(combined)-434(treatment\))-430.8(twice)-429.4(a)]TJ
0 -1.1116 TD
[(week)-520.2(while)-520.4(still)-518.4(maintaining)-523(conventional)-524(treatment.)-525.3(All)]TJ
T*
[(patients)-397.2(had)-396.1(to)-394(keep)-398.4(using)-397.1(their)-398.6(anti-parkinsonian)-402.6(medica-)]TJ
0 -1.1174 TD
[(tions,)-343.1(but)-343.3(the)-344.4(method)-343.2(of)-342(delivery)-345.4(or)-342(dosage)-348.6(could)-340.9(be)-343.2(chan-)]TJ
0 -1.1116 TD
[(ged)-332.8(during)-335(the)-332.9(study)-333.7(period.)]TJ
1.0137 -1.1116 TD
[(Study)-656.3(participants)-662.1(underwent)-658.3(stimulation)-660(of)-658.8(10)-658.8(acu-)]TJ
-1.0137 -1.1116 TD
[(puncture)-374.1(points)-369.5(using)-374.1(acupuncture)-374(and)-373.1(BVA)-374.7(twice)-371.8(a)-370.9(week)]TJ
0 -1.1174 TD
[(for)-527.4(12)-526.3(weeks.)-524.6(The)-529.8(initial)-527.9(assessment)-533.5(was)-523.5(repeated)-531.9(after)]TJ
0 -1.1116 TD
[(conventional)-380(treatment)-383.6(\(12)-383.4(weeks\))-378.2(and)-384.6(after)-382.3(the)-379(combined)]TJ
T*
[(treatment)-521.8(\(24)-521.6(weeks\))-528(\(Fig.)-520.4(1\).)-518.2(At)-521.6(the)-523(conclusion)-526(of)-520.5(the)]TJ
0 -1.1174 TD
[(study,)-423.6(the)-430.8(patients)-431.8(were)-428(interviewed)-431.5(by)-428.4(using)-425.9(open-ended)]TJ
0 -1.1116 TD
[(questions)-385.3(to)-382.5(explore)-384.5(subjective)-383.3(changes)-385.4(in)-382.5(their)-387(symptoms)]TJ
T*
[(after)-336.2(the)-332.9(combined)-335(treatment.)]TJ
/F9 1 Tf
8.9663 0 0 8.9663 310.8472 341.5747 Tm
(Interventions)Tj
/F5 1 Tf
9.843 0 0 9.843 320.8251 325.1338 Tm
.0182 Tc
[(All)-582(i)-.3(nterventions)-581.7(were)-577.3(performed)-581.9(by)-576.1(one)-577.3(doctor)-576.1(o)-.2(f)]TJ
-1.0137 -1.1116 TD
.0188 Tc
[(Korea)5(n)-339.4(medicine)-340.6(with)-339.4(m)5(o).4(re)-340.6(than)-339.4(10)-339.4(years)-339.2(o).4(f)-339.4(e)5(xperience.)]TJ
T*
[(Patien)6.2(t).3(s)-241.3(r).5(eceived)-241.5(t)6.1(reatments)-241.3(w)-.4(ith)-235.7(BVA)-242.4(a)-.7(nd)-235.7(acupuncture)-242.7(a)5(t)]TJ
0 -1.1174 TD
.0183 Tc
[(10)-293.8(acupuncture)-300.7(po)5.7(ints)-299.4(\(bilateral)-294(G)-.9(B20,)-296.2(LI4,)-296.2(GB34,)-296.2(ST36,)]TJ
0 -1.1116 TD
0 Tc
[(a)-19.5(n)-18.4(d)-225.7(L)0(R)24.4(3)16.2(\))-196.9(t)0(w)25.6(i)0(c)25.3(e)-198.1(a)-198.1(w)15.3(ee)24.3(k)-196.9(f)0(o)26.6(r)-196.9(12)-186.5(w)15.3(e)15(ek)25.4(s)-196.7(\()0(t)26.5(o)0(t)26.5(a)15(l)-197.1(o)0(f)-186.5(2)16.2(4)-196.9(s)0(e)25.6(s)0(s)27(i)0(o)26.5(n)16.2(s\))26.8(.)-199.3(B)15.2(ee)]TJ
T*
[(v)16.2(e)15(no)26.6(m)15(,)-170.5(0.)24.3(1)-150.8(m)15(l)-168.3(d)0(i)26.5(l)16.1(ut)26.5(e)15(d)-173.9(t)16.1(o)-168.1(0.)24.3(0)16.2(0)16.2(5)0(%)-158.8(i)16.1(n)-173.9(n)16.2(o)16.2(r)0(m)25.4(a)15(l)-168.3(s)0(a)25.6(l)0(i)26.3(n)16.2(e)-175.1(\()16.2(Y)15.3(u)0(m)25.4(i)16.1(l)-174(F)16.3(a)15(r)0(m)25.4(,)]TJ
0 -1.1174 TD
[(H)15.3(w)15.3(a)0(s)25.6(u)0(n)26.6(,)-170.5(Je)25.6(o)16.2(n)0(n)26.6(a)15(m,)-161.3(K)15.3(o)0(r)26.6(e)15(a\))25.5(,)-170.5(w)0(a)24.6(s)-173.7(i)16.1(n)0(j)26.5(e)15(ct)25.3(e)15(d)-173.9(in)26.5(t)16.1(o)-173.9(e)15(a)0(c)24.3(h)-173.9(p)16.2(o)16.2(i)0(n)26.5(t)16(;)-174(s)0(t)26.7(e)15(ri)26.5(le)25.3(,)]TJ
0 -1.1116 TD
.0117 Tc
[(d)4.8(i)-1(sp)4.8(os)5(abl)4.7(e)-2.1(,)-400.7(s)-.7(t)4.7(a)-2.1(in)4.8(less)-403.9(st)4.7(eel)-404.2(a)-2.1(cu)]TJ
12.6138 0 TD
.0095 Tc
[(punc)-4.3(ture)-407.5(ne)-4.3(edle)-4.3(s)-406.1(\()2.7(diam)-4.3(eter,)]TJ
-12.6138 -1.1116 TD
0 Tc
[(0.)24.3(25)-152(m)15(m)0(;)-360.7(l)0(e)13.8(n)0(g)20.8(t)0(h)20.7(,)-366.3(30)-152(m)15(m)-370.9([D)20(on)15.1(gb)20.8(an)19.7(g,)-355.9(Bo)14(ry)20.9(eo)19.7(ng)20.8(,)-372.1(C)0(h)19.8(u)0(n)20.8(g)0(n)20.8(a)0(m)18.5(,)]TJ
0 -1.1174 TD
[(Ko)20(re)19.7(a])19.7(\))-214.2(w)0(e)18.8(r)0(e)-210.7(i)0(n)20.7(s)0(e)19.9(r)0(t)20.7(e)0(d)-205(i)0(n)20.7(t)0(o)-203.9(t)0(h)15(e)-215.4(po)20.8(in)20.7(ts)-203.7(li)20.6(st)15.1(ed)-204.9(ab)19.7(ov)20.8(e)-215.4(t)0(o)-203.9(a)-215.4(de)19.7(pt)20.7(h)-214.2(o)0(f)]TJ
0 -1.1116 TD
[(1.)24.3(0)15.1(1.)24.3(5)-156.6(c)0(m)-200.4(a)0(n)13.9(d)-208.4(ro)20.9(ta)19.6(te)19.5(d)-208.4(a)0(t)-205.1(2)-156.6(Hz)-200.1(fo)20.9(r)-214.2(1)0(0)-198(s)0(e)19.9(c)0(o)19.7(n)0(d)20.8(s)-214(to)-198.2(ac)18.5(hi)20.7(ev)19.7(e)]TJ
/F10 1 Tf
22.1288 0 TD
[(de)-204.9(qi)]TJ
/F5 1 Tf
1.9122 0 TD
(,)Tj
-24.041 -1.1116 TD
[(th)20.7(e)-186.6(s)0(e)19.9(n)0(s)21(a)0(t)13.8(i)0(o)20.7(n)-185.4(fe)19.7(lt)-175.2(by)-175(th)20.7(e)-186.6(p)0(a)13.9(t)0(i)20.6(e)0(n)19.7(t)-185.5(wh)20(en)-176.2(th)20.7(e)-186.6(a)0(c)18.5(u)0(p)15.1(u)0(n)20.8(c)0(t)19.5(u)0(r)20.9(e)-186.6(ne)19.7(ed)19.7(le)-176.3(is)]TJ
ET
q
336.928 0 0 53.461 136.573 123.42 cm
/Im1 Do
Q
BT
/F7 1 Tf
9.845 0 0 9.845 59.7543 106.6393 Tm
[(FIG.)-382.8(1.)]TJ
/F5 1 Tf
4.1634 0 TD
[(Research)-382(procedure.)-378.6(Conventional)-384.3(tr)20.9(ea)18.7(tm)19.7(en)19.9(t:)-307.5(Pa)20.1(ti)20.7(en)19.9(ts)-307.2(ma)18.7(in)20.9(ta)19.7(in)20.9(ed)-308.4(th)20.9(ei)19.7(r)-317.7(a)0(n)19.9(t)0(i)20.7(-)0(p)21(a)0(r)19.9(k)0(i)20.9(n)0(s)15.5(o)0(n)21.1(i)0(a)19.7(n)-312(me)18.7(di)15.1(ca)18.7(ti)20.7(on)-301.4(wi)14.3(th)20.9(ou)21(t)-312.1(a)0(n)19.9(y)]TJ
-4.1634 -1.0077 TD
[(ad)19.9(di)15.1(ti)20.7(on)21.1(al)-314.3(tr)20.9(ea)18.7(tm)19.7(en)19.9(t)-323.6(f)0(o)21(r)-323.5(12)-312.9(we)19.1(ek)19.9(s;)-313(co)19.9(mb)19.9(in)20.9(ed)-314.1(tr)20.9(ea)18.7(tm)19.7(en)19.9(t:)-313.3(Pa)20.1(ti)14.9(en)19.9(ts)-312.9(we)19.1(re)-314.1(tr)20.9(ea)18.7(te)19.7(d)-323.5(w)0(i)20.1(t)0(h)-313.1(a)0(c)18.7(u)0(p)21.1(u)0(n)21.1(c)0(t)19.7(u)0(r)21(e)-324.6(an)19.9(d)-323.5(b)0(e)19.9(e)-324.6(ve)19.9(no)21.1(m)-324.6(a)0(c)18.7(u)0(p)21(u)0(n)21.1(c)0(t)19.7(u)0(r)21.1(e)]TJ
0 -1.0135 TD
[(tw)14.3(ic)19.7(e)-180.7(a)-180.7(w)0(e)19.1(e)0(k)-170.2(w)0(h)20.2(i)0(l)20.7(e)-180.7(ma)18.7(in)20.9(ta)19.7(in)20.9(in)15.1(g)-179.5(t)0(h)20.9(e)-180.7(co)19.9(nv)21.1(en)19.9(ti)20.7(on)21.1(al)-170.3(tr)15.1(ea)18.7(tm)19.7(en)19.9(t;)-169.3(as)20(se)20.1(ss)15.6(me)18.7(nt)20.9(:)-179.7(A)0(l)20.1(l)-179.7(pa)19.9(ti)20.7(en)19.9(ts)-174.7(we)19.1(re)-170.2(as)20.1(se)20(ss)21.4(ed)-175.9(us)21.2(in)20.9(g)-179.5(t)0(h)20.9(e)-180.7(Un)20.2(i)21(ed)-170.2(Pa)14.3(rk)21(in)20.9(so)21.2(n)21.1(s)]TJ
T*
[(Di)14.3(se)20.1(as)20.1(e)-232.5(R)0(a)18.9(t)0(i)14.9(n)0(g)-220.8(S)0(c)20.1(a)0(l)19.7(e)-238.3(\(U)20.2(PD)20.4(RS)20.2(\),)-229(th)20.9(e)-232.5(P)0(a)20.1(r)0(k)21(i)0(n)15.1(s)0(o)21.2(n)0()21.1(s)-236.9(Di)20.1(se)20(as)20.1(e)-238.3(Q)0(u)20.2(a)0(l)19.7(i)0(t)20.7(y)-237.1(of)-220.8(Li)19.7(fe)-227.7(Qu)20.2(es)20(ti)20.7(on)21.1(na)14.1(ir)20.9(e)-232.5(\()0(P)21.2(D)0(Q)13.6(L)0(\))19.9(,)-233.7(th)20.9(e)-232.5(s)0(p)15.5(e)0(e)18.7(d)-231.3(an)19.9(d)-237.1(n)0(u)21(m)0(b)19.9(e)0(r)-222(o)0(f)-226.6(s)0(t)21(e)0(p)19.9(s)]TJ
T*
[(re)14.1(qu)21.1(ir)20.9(ed)-412(to)-416.8(wa)19.1(lk)-411(20)-145.9(m,)-414.4(th)20.9(e)-422.5(B)0(e)18.9(c)0(k)-417.8(D)0(e)19.1(p)0(r)21.1(e)0(s)20.1(s)0(i)21(o)0(n)-416.6(I)0(n)21(v)0(e)19.9(n)0(t)20.9(o)0(r)21.1(y)-427.1(\(B)20.1(DI)20.2(\),)-413.2(an)19.9(d)-421.4(p)0(o)15.3(s)0(t)21(u)0(r)21(a)0(l)-412.2(s)0(t)15.3(a)0(b)19.9(i)0(l)20.7(i)0(t)20.7(y)-421.4(me)18.7(as)14.3(ur)21.1(ed)-412(by)-410.8(co)14.1(m)15.1(p)0(u)15.3(t)0(e)19.7(r)0(i)20.9(z)0(e)18.7(d)-421.4(dy)21.1(na)19.9(mi)19.7(c)]TJ
0 -1.0077 TD
[(po)15.3(st)21(ur)21(og)21.1(ra)19.9(ph)21.1(y.)]TJ
/F3 1 Tf
8.9663 0 0 8.9663 59.7543 749.7069 Tm
[(ACUPUNCTURE)-340.1(AND)-337.2(BEE)-333.7(VENOM)-338.4(ACUPUNCTURE)-340.1(FOR)-334(IDIOPATHIC)-338.3(PARKINSONS)-334.1(DISEASE)-7866.5(599)]TJ
ET
endstream
endobj
38 0 obj
<>stream
Adobe d C
p
s !1AQa"q2B#R3b$r%C4Scs5D'6Tdt&
EFVU(eufv7GWgw8HXhx)9IYiy*:JZjz ? ?^Em*=;ORzZGZwɭ|me"Q܁^MmrJ4$juܷW{+e.GbGwp6*iJO[{M?S4vPnd-刔Gf?IɗZEƳmXMZ\D?ʓhoEY>
e
r.4I55)thk)qN&_=y1CrGR_WW^˗OMco#XeX1