Tag: Immunology
The Sleep and Immunity: Crosstalk in Health and Disease
All of our systems are interrelated. This article looks in depth at the effect of sleep on the immune system. Very topical during or surviving from a pandemic! Sleep can affect how sick you get if infected, whether you get infected, and how well your immunization works for you. More on the topic of sleep…
Read MoreElectroacupuncture improves gut barrier dysfunction in prolonged hemorrhagic shock rats through vagus anti-inflammatory mechanism
The most important novel findings from this study are that when delayed resuscitation is inevitable during emergency situations such as hemorrhagic shock occurring in war without sufficient fluids, electroacupuncture at ST36 can be performed and it can successfully attenuate systemic inflammation, decrease gut injury and permeability and improve blood pressure and outcomes, which is consistent…
Read MoreVagal Afferent Modulation of Nociception
Vagal Afferent Modulation of Nociception A Randich 1, G F Gebhart Affiliations expand PMID: 1327371 DOI: 10.1016/0165-0173(92)90009-b Abstract Chemical, electrical or physiological activation of cardiopulmonary vagal (cervical, thoracic or cardiac), diaphragmatic vagal (DVAG) or subdiaphragmatic vagal (SDVAG) afferents can result in either facilitation or inhibition of nociception in some species. In the rat, these effects depend upon vagal afferent input…
Read MoreInvolvement of TRPV1 Channels in Energy Homeostasis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079260/ Front Endocrinol (Lausanne). 2018; 9: 420. Published online 2018 Jul 31. doi: 10.3389/fendo.2018.00420 PMCID: PMC6079260 PMID: 30108548 Involvement of TRPV1 Channels in Energy Homeostasis Stewart Christie,1 Gary A. Wittert,1,2 Hui Li,1,2 and Amanda J. Page1,2,* Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract The ion channel TRPV1 is involved in a wide range…
Read MoreMast Cell-Mediated Mechanisms of Nociception
This is an exhaustive look at the different mechanisms involved in mast cell activation and how they might relate to different pain conditions. Mast cells are released with acupuncture needling and can contribute to positive feedback loops to quash hyper sensitivity and auto immune conditions. This article has mast cells playing a role in pain…
Read MoreEffect of electroacupuncture on SIRT1/NF-κB signaling pathway in adipose tissue of obese rats
This is a key article. Because Chinese Medicine has had longevity as part of its charter forever, this may be a piece of evidence that shows the science behind why this might be true. A brief description of the science behind Sirtuin1 follows in this abstract. There’s a caveat at the end of the wikipedia…
Read MoreInflammation: From Depression to Dementia Inflammation is the New Frontier
Another “welcome to my world” article about how inflammation is related to mental conditions from depression to dementia. “The barrier between mind and body, for so long a dogmatic conviction, appears to be crumbling.” Of course, that is the relationship between mind and body has been a pillar of Chinese Medicine for Millennia. My own…
Read MoreIL-6: a cytokine at the crossroads of autoimmunity
I am linking to this as background for a writing project. Il-6 is mentioned quite a bit as part of the acupuncture cascade, so I want to learn more. I’m also trying to get up to date on Immunology, which basically barely existed when I was in med school. Highlights • IL-6 promotes development…
Read MoreEffect Of Moxibustion on HRV depends on Temperature
This article shows that after a threshold temperature on the forearm, there is more complexity in local blood flow, but also on HRV. I’m not sure how to use this information exactly. Moxibustion is not a modality that’s easy for me to use in the clinic. But I like the fact that they looked at…
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