Tag: Immunology

Health & Fitness

Immune and genetic aspects of asthma, allergy and parasitic worm infections: evolutionary links

This paper is over 10 years old, but it still has a lot to say.  I have yet to buy the pdf of the full paper. But it is a concise description of the concept of “old friends.”  When a person has  immunity to “old friends” such as Ascaris and Schistomona evolutionarily developed over millenia…

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Medical Research

Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system

Fascinating background material for my chapter on the Immune System Tieri P, Grignolio A, Zaikin A, et al. Network, degeneracy and bow tie. Integrating paradigms and architectures to grasp the complexity of the immune system. Theor Biol Med Model. 2010;7:32. Published 2010 Aug 11. doi:10.1186/1742-4682-7-32 Abstract Recently, the network paradigm, an application of graph theory to…

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Medical Research

Signal Transduction Pathways of Acupuncture for Treating Some Nervous System Diseases

This article is a fantastic resource that looks at the nitty gritty of multiple signaling pathways.  This is important because these pathways are the focus of research and pharmaceuticals companies to target these pathways for immune functions, inflammation, and anti-aging. Evid Based Complement Alternat Med. 2019; 2019: 2909632. Published online 2019 Jul 11. doi: 10.1155/2019/2909632 PMCID: PMC6657648 PMID: 31379957…

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Medical Research

Toward the Existence of a Sympathetic Neuroplasticity Adaptive Mechanism Influencing the Immune Response. A Hypothetical View—Part I and II

  I monitor autonomic activity in the clinic during acupuncture treatment.  I use heart rate variability (HRV) and concentrate mostly on vagal activity or parasympathetic activity.  But I’ve been impressed with the strength of the correlation of sympathetic activity with treatment, usually decreasing, with acupuncture and TAVNS also.  I wasn’t aware that there was a…

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Health & Fitness

Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week

J Am Coll Cardiol. Author manuscript; available in PMC 2019 Oct 23. Published in final edited form as: J Am Coll Cardiol. 2018 Oct 23; 72(17): 2071–2081. doi: 10.1016/j.jacc.2018.08.1043 PMCID: PMC6196735 NIHMSID: NIHMS1504204 PMID: 30336831 Inflammation, Immunity, and Infection in Atherothrombosis: JACC Review Topic of the Week Peter Libby, MD,1 Joseph Loscalzo, MD, PhD,1 Paul Ridker,…

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Health & Fitness

Anti-Cytokine Agents: Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis

Circ Res. Author manuscript; available in PMC 2020 Feb 1. Published in final edited form as: Circ Res. 2019 Feb; 124(3): 437–450. doi: 10.1161/CIRCRESAHA.118.313129 PMCID: PMC6386195 NIHMSID: NIHMS1517334 PMID: 30702995 Anti-Cytokine Agents: Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis Paul M Ridker, MD, MPH Author information Copyright and License information Disclaimer The publisher’s final…

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Health & Fitness

Targeting Residual Inflammatory Risk: A Shifting Paradigm for Atherosclerotic Disease

Front Cardiovasc Med. 2019; 6: 16. Published online 2019 Feb 28. doi: 10.3389/fcvm.2019.00016 PMCID: PMC6403155 PMID: 30873416 Targeting Residual Inflammatory Risk: A Shifting Paradigm for Atherosclerotic Disease Aaron W. Aday1,* and Paul M. Ridker2 Author information Article notes Copyright and License information Disclaimer This article has been cited by other articles in PMC. Go to: Abstract…

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Medical Research

Inflammation IL-6 , Electroacupuncture and HRV

This study, though older, is important because it connects the dots between vagal activity,  pro-inflammatory cytokines (Il-6), and gastric emptying.  It would be quite expensive to do this study in a human controlled trial.  This is where these animal models are so useful to expand our thinking on how acupuncture works. http://www.ncbi.nlm.nih.gov/pubmed/23848593 Neurogastroenterol Motil. 2013…

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Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743376/ Front Immunol. 2019; 10: 2090. Published online 2019 Sep 6. doi: 10.3389/fimmu.2019.02090 PMCID: PMC6743376 PMID: 31552038 Bee Updated: Current Knowledge on Bee Venom and Bee Envenoming Therapy Manuela B. Pucca,1,2,* Felipe A. Cerni,2,3 Isadora S. Oliveira,3 Timothy P. Jenkins,2 Lídia Argemí,2 Christoffer V. Sørensen,2 Shirin Ahmadi,2,4 José E. Barbosa,5 and Andreas H. Laustsen2,* Author information…

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Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720840/ Molecules. 2019 Aug; 24(16): 2997. Published online 2019 Aug 19. doi: 10.3390/molecules24162997 PMCID: PMC6720840 PMID: 31430861 Bee Venom: Overview of Main Compounds and Bioactivities for Therapeutic Interests Rim Wehbe,1,† Jacinthe Frangieh,1,2,† Mohamad Rima,3,4 Dany El Obeid,5 Jean-Marc Sabatier,6 and Ziad Fajloun1,7,* Author information Article notes Copyright and License information Disclaimer This article has been cited…

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